androgen insensitivity links

AIS Support Groups

List of AIS Support Groups around the world

AIS Support Group (UK)

AIS Links

CAIS Booklet

John Hopkins website

Androgen Insensitivity Syndrome GeneTests Link

Choosing the right gender

MRKH Links

MRKH UK Website

MRKH Organisation, Inc.

Congenital Adrenal Hypoplasia (CAH) Links

Klinefelter Syndrome Website

Non-AIS Specific Intersex Links

Intersex Society of North America (ISNA)

Bodies Like Ours (US)

Intersex Initiative

Hypospadias and Epispadias Association

AGSA - The Association of Genetic Support of Australasia

Genetic Support Network of Victoria

NSW Genetics Education Program

Human Genetics Society of Australasia

Miscellaneous Links

Andrology Australia

Anti-Discrimination Commission Queensland

David Reimer interview

Victorian Equal Opportunity & Human Rights Commission

Pharmaceutical Benefits Scheme

Queensland Health Freedom of Information Website

The Lesbian Gay Bisexual Trans Intersex Legal Service Inc.

Positive Living Centre, Adelaide

Self Help Queensland Inc (SHQ)

The National LGBT Health Alliance

glossary for androgen insensitivity

AIS: Androgen Insensitivity Syndrome. There are two forms known as Complete AIS (CAIS) and Partial AIS (PAIS).

amenorrhoea (alternate spelling amenorrhea): abnormal suppression or absence of menstruation

androgens: the general term for any one of a group of hormones which govern the development of the sexual organs and the secondary sexual characteristics of the male

axillary: underarm

carrier: a person that carries, but does not express, a gene for a particular recessive trait http://androgeninsensitivity.blogspot.com/

chromosomes: threadlike strands of DNA and associated proteins in the nucleus of cells that carry the genes and functions in the transmission of hereditary information

endocrinologist: a medical doctor who studies the endocrine system, hormones and disorders of the endocrine system


gonad: an organ that produces gametes (germ cells), especially a testis or ovary

gonadectomy: surgical removal of the gonads (sex glands). In AIS, this is the removal of the testes. http://androgeninsensitivity.blogspot.com/

HRT or Hormone Replacement Therapy: technically this is the replacement of both oestrogen (estrogen) and progestogen by tablet, injection or transdermal patch. Sometimes this term is used even though the only hormone being replaced is oestrogen.

inguinal hernia: A hernia is the protrusion of any organ through the wall of the cavity that holds it. In AIS, an inguinal hernia is the protrusion of the testes through the inguinal canal.

intersex state or intersexualilty: the condition resulting from faulty sex differentiation during the development of the foetus

Mullerian ducts: either of two embryonic tubes that become the uterine tubes, uterus and part of the vagina in the female and that form the prostatic utricle in the male

orchid: a plant that takes its name from the Greek word "orchis" which means "testes." Orchids were so named because of the resemblance of their root bulbs to testes. What emerges from this seemingly masculine looking root, however, is the beautiful flower known as an orchid. http://androgeninsensitivity.blogspot.com/

osteoporosis: a disease in which the bones become extremely porous, are subject to fracture, and heal slowly

phenotype: a person's physical characteristics as determined by the interaction between his or her genotype-quota of genes-and the environment

Wolffian duct: a duct in the embryo that becomes the vas deferens in the male and forms vestigial structures in the female

Undervirilized fertile male syndrome (Mild Androgen Insensitivity Syndrome)

Some AR mutations with mildly reduced sensitivity cause mild undervirilization. These men have normally formed internal and external genitalia but often a small penis. Androgenic body hair may be sparser than unaffected relatives. Ejaculate volume may be reduced, though sperm density is normal. Few examples of this variant of AIS have been reported, but unlike the previously listed phenotypes, many of these men are fertile. Also, individuals with this condition may experience gynecomastia during puberty.

Androgen Insensitivity Syndrome male or woman

Androgen Insensitivity Syndrome (AIS) video from youtube. Very good video about AIS disease . it is a genetical and complicate disease.

another interesting video about AIS : http://abcnews.go.com/video/playerIndex?id=5544655

Androgen Insensitivity Syndrome video

Androgen Insensitivity Syndrome information.. Androgen insensitivity video

Androgen insensitivity Links

Links for Androgen insensitivity informatin: at this web page you will see a list of links to additional sites related to Androgen Insensitivity Syndrome and more information about the syndrome.

Human Sex-differentiation Group in Lübeck
Standford.edu
Emedicine Article
Geneclinics

Types of androgens

A group of androgens, the "adrenal androgens" include all steroids to 19 carbon atoms, synthesized by the adrenal cortex, ie the outer portion of the adrenal gland, which operate as weak steroids or precursors steroids, including dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S) and androstenedione.

Apart testosterone, androgens include:
The dehydroepiandrosterone (DHEA): a steroid hormone produced from cholesterol in the adrenal cortex, which is the main precursor of natural estrogen. DHEA is also known déhydroisoandrostérone or déhydroandrostérone.
The androstenedione (andro): an androgenic steroid that is produced by the testes, adrenal cortex and ovaries. While androstenedione is converted metabolically testosterone and other androgens, they are also the structure of mother estrone. The use of androstenedione as a supplement to the sport or the club was banned by the International Olympic Committee and other sports organizations.

The androstenediol: steroid metabolite that is supposed to act as the primary regulator of gonadotropin secretion.
The androsterone: chemical byproduct created during the degradation of androgens, or derived from progesterone, which also exerts effects virilization minors, but with one-seventh of the intensity of testosterone. It is present in quantities roughly equal in plasma and urine of men and women.

Dihydrotestosterone (DHT): a metabolite of testosterone which is a more potent androgen in that it binds more strongly to the androgen receptor.